Clinical Trials Archives - Page 2 of 2 - AZ Clinical Trials

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When it comes to detecting and identifying the severity of liver disease, the gold standard is typically a liver biopsy. Newer technological advances have paved the way for other non-invasive options such as the fibroscan. It comes without any risks. It’s also cheaper, quicker, and more accurate. If you are at risk for or already have liver disease, your overall health depends on early detection and regular monitoring. Both are just some of the reasons your liver can benefit from fibroscan technology.

Time-Tested, Trusted Technology.

For decades, ultrasound technology has enabled us to see a growing baby in the womb and many other medical uses. Fibroscan technology harnesses this technology to measure the stiffness of the liver. As the sound waves pass through the liver, the device measures how fast they go. The faster they move, through it, the greater the degree of fibrosis or stiffness. There are over 100 types of liver disease. However, most will follow the same path of progressive damage.

Don't treat your liver like chopped liver

Chronic inflammation as the body repeatedly attempts to heal the liver ironically ends up doing the exact opposite. In a healthy liver, the body produces and transports collagen to repair the damage. It does this by surrounding healthy tissue and strengthening it. With liver disease, more collagen is sent than needed. It builds up between liver cells, binding with other proteins forming scar tissue or fibrosis. The scarring can reduce or stop blood flow, starving and killing healthy cells. More scarring occurs, eventually replacing more and more healthy cells with non-function performing scar tissue.

Early Detection, Progression Monitoring, Lifesaving. 

The liver is a regenerative organ and can heal itself even well into the later stages of liver disease. Ideally, those at risk of developing liver disease would work with their doctor to proactively monitor their liver health. By measuring the degree of stiffness, fibroscan technology can detect the presence of liver issues. Similarly, it is an essential monitoring tool for managing disease progression, stagnation, and regression.

There isn’t a limit to the number of times your provider can perform a fibroscan. In turn, this allows for real-time results measuring how well lifestyle modifications and other therapies are working. The best part is that along with typical lab tests, fibroscan technology continues reducing the need for liver biopsies. Ultimately, it is improving, prolonging, and easing the management of the lives of liver disease patients. Your liver really can benefit from a fibroscan!

Free fibroscan for adults at risk

Arizona Liver Health offers FREE fibroscans for adults at risk of developing liver disease. Based on the exam results, you may be eligible to participate in currently enrolling research studies evaluating potential new options for liver diseases like NASH. Take control of your liver health today! Schedule your free screen by calling (480) 470-4000 or requesting an appointment online.

Sources:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594956/

https://hemaware.org/bleeding-disorders-z/do-wave

https://www.hje.org.uk/benefits-fibroscan-liver-health/


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Regular physical activity is the cornerstone of a healthier body and quality of life. It also has been proven to reduce your risk of chronic conditions like type 2 diabetes, heart disease, and dementia. Physical activity and liver disease go hand in hand. It could even save your life.

Exercise and the Effect on the Liver

Exercises focusing on your cardiovascular system have a positive influence on blood oxygenation. These activities increase your heart rate and change your breathing pattern. In turn, this increases the amount of oxygen you take in and quickly delivers oxygen to your vital body organs, such as your liver. Exercise also reduces stress on the liver, raises energy levels, and helps prevent obesity, a risk factor for liver disease. Other benefits include:

  • Maintaining a healthy weight helps prevent developing conditions that can lead to liver damage. Examples are fatty liver, elevated blood glucose, diabetes, and elevated blood insulin.
  • Regular exercise helps ease the depressive effects by triggering the release of endorphins. Exercise also helps balance out neurotransmitter levels. Together, these promote a sense of well-being and strength.
  • In addition to improving the delivery of oxygen to vital organs, regular exercise improves the efficiency of the cardiovascular system. The outcome helps greatly improve energy levels.

Scar tissues form in the liver because of the progressive damage. Ultimately, fibrous scar tissue replaces healthy liver tissue leading to chronic damage (cirrhosis). Cirrhosis is often accompanied by loss of muscle mass and strength. Therefore, for those already with liver disease, physical activity may not only be beneficial but interventional too.

Life-Saving Benefits Discovered Thanks to Research Studies

The fact that exercising comes with many benefits is not some new revolutionary concept. Most of us know it’s good for you and maintaining a healthier lifestyle. A recent clinical research study proved a ground-breaking theory in the correlation of physical activity and cirrhosis-related deaths. It showed a 73% reduction in mortality risk when patients regularly walked during the week. When strength training was combined with walking, the risk was even less.

Liver disease research

As we continue learning more about liver disease and what causes it to develop, we increase community awareness and improve the lives of those living with this condition. A greater understanding of the disease also equips scientists and researchers with the tools necessary to improve management options. Arizona Liver Health is seeking participants to join enrolling studies for individuals diagnosed with NASH. NASH is a more severe form of non-alcoholic fatty liver disease and a growing epidemic in America. Learn more about how you can get involved by calling us at (480) 470-4000 or stopping by our website.

References:

https://www.cdc.gov/chronicdisease/resources/infographic/physical-activity.htm#:~:text=Regular%20physical%20activity%20helps%20improve,depression%20and%20anxiety%2C%20and%20dementia.

https://www.liversupport.com/exercise-for-chronic-liver-disease/

https://www.livestrong.com/article/287774-the-effect-of-exercise-on-liver-function/


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Accurate vaccine information is critical now that there are authorized and recommended COVID-19 vaccines in the U.S. Knowing which sources of information you can trust can be complex. You may have heard claims about the vaccines on social media or from family or friends. Or the rapid development and approval of these vaccines may have made you hesitant about their safety or effectiveness. The truth is, vaccines are the best chance we have of ending COVID-19. It’s time to set the record straight and get the facts behind 5 of the most common myths about COVID-19 vaccines.

Spread facts not fear. Explore COVID-19 research studies

Top 5 Myths Busted

Myth #1: The COVID-19 vaccine was rushed, so it can’t be safe.

Truth: The CDC said it best, “COVID-19 vaccines are safe and effective. COVID-19 vaccines were evaluated in tens of thousands of participants in clinical trials. The vaccines met FDA’s rigorous scientific standards for safety, effectiveness, and manufacturing quality needed to support emergency use authorization (EUA). “

Millions of people in the United States have received COVID-19 vaccines, and these vaccines will undergo the most intensive safety monitoring in U.S. history. This monitoring includes using both established and new safety monitoring systems to ensure that COVID-19 vaccines are safe.

Myth #2: It will alter your DNA.

Truth: Both mRNA and viral vector COVID-19 vaccines deliver instructions (genetic material) to our cells to fight COVID-19. However, it never enters the nucleus of the cell, where we keep our DNA. The genetic material in the vaccines cannot affect or interact in any way with our DNA.

Myth #3: If you’ve already had COVID-19, you don’t need to get the vaccine.

Truth: There are severe health risks associated with COVID-19, and it is possible to get reinfected. Therefore, individuals may benefit from getting the vaccine.

Myth #4: The vaccine will deliver a microchip into your body.

Truth: This myth was started after a comment made by Bill Gates about vaccine registry and wasn’t even referring to a microchip. There is no vaccine microchip, and the vaccine will not gather any personal information or track people.

Myth #5: It affects fertility.

Truth: Currently, there is no evidence that COVID-19 vaccination causes any problems with pregnancy, and there is no evidence that fertility problems are a side effect of any vaccine, including COVID-19 vaccines.

The Truth is Out There

Spread hope not covid

When researching the COVID-19 vaccines on the internet, check that the information comes from a credible source that is updated regularly. Millions of people have been affected by this virus, but together, we can help to end COVID-19. Arizona Clinical Trials offers FREE COVID-19 screenings and conducts research studies looking into potential new ways to treat and prevent it. To learn how you can get involved, call 480-360-4000, or visit our website.

References:

https://www.hopkinsmedicine.org/health/conditions-and-diseases/coronavirus/covid-19-vaccines-myth-versus-fact

https://www.cdc.gov/coronavirus/2019-ncov/vaccines/facts.html

https://www.mayoclinichealthsystem.org/hometown-health/featured-topic/covid-19-vaccine-myths-debunked


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Indeed, the liver is a resilient, amazing organ. However, it isn’t indestructible, and its health is vital to your body’s overall wellness. Anyone can develop liver disease, so Arizona Liver Health has 10 tips to keep your liver happy and healthy.

10 Tips for Overall Liver Health

Take good care of your liver and your liver will take good care of you

1. Maintain a healthy weight.

Even those somewhat overweight are in danger of having a fatty liver that can lead to non-alcoholic fatty liver disease (NAFLD). Losing weight can play a vital role in helping to reduce liver fat.

2. Eat healthily.

Avoid foods high in calories, sugars, and saturated fats. A well-adjusted diet includes fresh fruits, vegetables, whole-grain breads, rice, and cereals. Monounsaturated and polyunsaturated fats are good fats. They are found in vegetable oils, nuts, seeds, and fish are “good” fats. Hepatitis A is contracted from contaminated food and water. Avoid raw or contaminated seafood or shellfish to be safe.

3. Exercise regularly.

Exercising consistently (30 minutes per day, 5 days a week) helps burn triglycerides for fuel. It can also reduce liver fat.

4. Keep chronic conditions managed.

Conditions such as diabetes, high blood pressure, and high cholesterol are major risk factors for fatty liver disease. Keeping them under reasonable control with diet can help limit and prevent liver damage.

5. Limit alcohol use.

Overindulging in alcohol can damage or destroy liver cells and scar your liver. Talk to your doctor about what the right amount of alcohol is for you.

6. Cut down smoking or stop smoking. 

Smoking has been linked to liver cancer and can also enhance the toxic effects that some medications have on the liver.

7. Practice safe sex.

Having unprotected sex or sex with multiple partners increases your risk of developing hepatitis B and hepatitis C.

8. Wash your hands.

Use soap and warm water immediately after using the bathroom or changing a diaper. Also before preparing or eating food.

9. Follow given directions on all medications.

You can harm your liver when you take medications incorrectly or by taking too much. Always let your doctor know about any over-the-counter medicines, supplements, and natural remedies that you use.

10. Get available hepatitis vaccinations.

Currently, there are vaccines for hepatitis A and hepatitis B. There is not a vaccine for hepatitis C.

Arizona Liver Health is committed to advancing options for liver disease patients through the research studies we conduct. Volunteers participating in clinical research make these advancements possible. When you have liver disease, and you join a study, you prioritize your health by learning more about your condition and potentially gaining access to new therapies not publicly available.

Don't leave your liver to fend for itself

To see how you can get involved in one of our enrolling liver studies, call (480) 470-4000, or visit our website.

References:

https://www.healthxchange.sg/digestive-system/liver/tips-healthy-liver

https://liverfoundation.org/13-ways-to-a-healthy-liver/

 


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thoughAfter a diagnosis of COVID-19, most patients with mild cases return home to quarantine and begin recovery. The thought may sound daunting, but don’t worry. With the proper precautions and knowing the warning signs, you do it. When treating mild cases of COVID-19, you are safer at home.

Caring for Yourself, Caring for Others

Whether you are caring for yourself or a loved one, there are a few things to keep in mind when recovering at home. Make sure to follow all safety protocols because the safety of the patient and caregiver is equally important.

Protecting others also means protecting yourself explore COVID-19 research studies today

  • Recovery Area
    • The patient should have a separate room with private bathroom access, if possible. If not, a sectioned area in a room will work. The bathroom would need to be sanitized after each use as well.
  • Protect Yourself and Others
    • A person must be isolated in quarantine for up to 10 days after the first symptoms began and 24 hours after being fever-free. Depending on the person recovering, the doctor may require a longer time.
    • Use a face mask
    • Wash your hands often
    • Cough into a tissue that you throw away immediately
    • Clean frequently touched surfaces often
    • Don’t share personal items, like dishes, towels, or bedding. Wash all items thoroughly.
  • Managing Symptoms
    • Take Tylenol to help reduce fevers
    • Stay hydrated by drinking water or juice
    • Resting will give your body the energy it needs to fight off the virus

Warning Signs

Call 911 immediately if you are having a hard time waking the patient up or they are showing any of the other warning signs:

  • Breathing trouble
  • Chest pain or pressure that is not alleviated
  • New confusion
  • Bluish color of lips or face
  • Inability to stay awake

COVID-19 Positive Adults Research

Clinical research studies help develop safe and effective ways to diagnose, treat, and prevent conditions like COVID-19. Research studies are why we have vaccines and other therapies available to help patients beat the virus. Without volunteers participating in research studies, these advancements wouldn’t be possible.

The lasting effects of COVID-19 are still unknown, COVID-19 research

Though we’ve come a long way, the battle is far from over. A diagnosis of COVID-19 can often come with an overwhelming sense of helplessness. But as research continues, everyone willing and able can help in the fight to end COVIID-19. If you have a positive diagnosis of COVID-19 within the last 96 hours, research studies here at Arizona Clinical Trials may be an option. Contact us at 480-360-4000 to learn more, or visit our website.

References:

https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/treating-covid-19-at-home/art-20483273

https://www.umms.org/coronavirus/what-to-know/treat-covid-at-home

 


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January 12, 2021 Clinical Researchliver0

Performing over 5,000 vital functions to sustain life and regeneration are some of the liver’s most remarkable features. It truly is an extraordinary organ, but it is not invincible. The celebrations of the holidays can add extra strain to your liver. If you have liver disease, these overindulgences can cause lasting effects. It’s the new year, but you have the same liver. While you are making your resolutions, consider a new diet to keep your liver healthy.

Your Liver’s Depending on You

The liver filters everything you eat and drink, and that is absorbed into your body. It can’t control what you put into it, but you can control how well it functions. Chronic alcohol consumption and foods high in saturated fats and processed sugars take a toll on the liver. These cause some of the most common liver conditions, such as alcohol and non-alcohol related fatty liver diseases.

Mediterranean diet foods, liver health, clinical research

Each liver patient has individual diet needs, so talk with your doctor about what’s right for you. Here are some general tips everyone’s liver can benefit from:

Foods good for the liver in addition to a balanced diet:

  • Coffee– Lowers the risk of cirrhosis, or permanent liver damage, in people with chronic liver disease.
  • Grapefruit– Grapefruit contain antioxidants that naturally protect the liver from injury.
  • Blueberries and Cranberries– Consuming these fruits for 3–4 weeks has been shown to protect the liver from damage.
  • Foods High in Fiber– Fiber helps your liver work at an optimal level.
  • Drink Plenty of Water– Water helps your liver function better by keeping your body hydrated.

Foods to avoid:

  • Any foods high in saturated fats
  • Those containing high levels of sugar and salt
  • Stay clear of fried foods, including fast food restaurant meals
  • Raw or undercooked shellfish should be avoided as well
  • If you are allowed alcohol, limit to one drink per day

The Silent Killer

Liver disease is progressive and typically takes years to develop. Often, there are no noticeable signs of an issue until the later stages. Diabetes, alcoholism, and obesity are the top risk factors. If you’re at risk, schedule a FREE fibroscan to check your liver health with us today. Fibroscans are a quick, non-invasive, painless scan that can determine if you have nonalcoholic steatohepatitis (NASH) or other fatty liver diseases. If your results indicate an abnormal function, our staff will discuss enrolling you in one of our liver disease studies here at Arizona Liver Health.

Liver inflammation and liver cell damage equal NASH, clinical research

Clinical research studies and the volunteers who participate in them make advancements in liver patients’ healthcare possible. To learn how you can get involved, call us at (480) 470-4000, or visit our study listing on our website.

References:

https://www.healthline.com/nutrition/11-foods-for-your-liver#TOC_TITLE_HDR_2

https://liverfoundation.org/for-patients/about-the-liver/health-wellness/nutrition/?gclid=CjwKCAiAoOz-BRBdEiwAyuvA69fghB4XiYIBdlbZL4zIf8PEl2b-ju8gvq3IdkqgcN7Kl6VEn4gf6hoCNO0QAvD_BwE


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November 10, 2020 Clinical ResearchCOVID-190

When the coronavirus pandemic hit, we cleared store shelves to prepare for what we feared was the worst. Families of healthcare workers, emergency responders, and other high-risk positions set up decontamination protocols in their homes in hopes of avoiding infection. Unfortunately, COVID-19 can still hit your household, despite all precautions. With a little preparation and determination, your family can get through it in the safest possible way.

Challenges of a COVID-19 Household

When someone is diagnosed in your family, the main thing is isolating them to prevent the virus from spreading. However, space and their function in the family role can make this a real challenge, among other things. Tasks shift from two to one, which puts pressure on the other partner who is likely already maxed out. This is true especially if there are children involved. Stress and emotions can build up for who it all falls on, and fear and guilt in the sick family member. The challenges may vary from home to home, but it’s tough any way you look at it.

Separate but Unified

Woman with mask, COVID-19 clinical research

Dealing with a loved one who has COVID-19 can be a scary experience. Even though you are separated from your loved one, you can help them get better and keep everyone else safe by staying the course. There are many things to remember when it comes to taking care of someone with COVID-19. We understand that everyone’s situation is different, but these can be used as a guide to get started and can be modified:

  • Function as a Unit: Identify one person who isn’t in the high-risk categories to care for the sick person. A separate person should be responsible for family members who need help with daily tasks like bathing, cleaning, and eating.
  • Separate Space: Pick a sick room and bathroom. If this cannot be achieved, separate a space in a shared room by a divider, and maintain 6 feet of distance at all times. The sick person should clean a shared bathroom after each use. All shared areas should be well-ventilated and cleaned frequently.
  • Keep Your Distance: Maintain 6 feet away from those who are sick at all times. Ill family members should not prepare food and should eat separately from others.

Lastly, don’t forget to take care of you. Reach out if you are overwhelmed or need help so you can get the support needed.

Changing the Future of COVID-19

Having COVID-19 and being in isolation can make you feel like a burden as you struggle to let others care for you. It’s hard to ride out not only the illness symptoms themselves but also complete quarantine after. Just keep in mind that your most significant role is keeping your family safe. By separation, you are doing that.

African American woman wondering, positive covid-19 test, clinical research

Researchers and other health experts have all hands-on deck as they work to find ways to diagnose, treat, and prevent COVID-19. Clinical research studies are being conducted right now, which are looking into some of the promising options in the fight against COVID-19. The volunteers participating in studies make this possible. If you or a loved one have COVID-19, you have a unique opportunity to change the virus’s future. To learn if volunteering in COVID trials here at Arizona Clinical Trials is right for you, visit our website for more information, or call (480) 360-4000.

References:

https://www.cdc.gov/coronavirus/2019-ncov/daily-life-coping/living-in-close-quarters.html


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September 15, 2020 Clinical ResearchCOVID-190

By now, most people have a backup mask in their vehicle, pocket, or purse, and sanitizer readily available. Staying six feet away has become 2nd nature, and asking, “Who’s going?” has taken on a whole new meaning. Many see their loved ones less, and some haven’t seen them since this all started. Thus, is life in the coronavirus pandemic. COVID-19 has filtered into almost every aspect of our lives, with 6,503,030 total cases in the United States alone. The impact of COVID-19 reaches deep, and its changes continue to shape daily routines and life as we know it.

The Trail of Change

COVID-19, social distancing

Though some have fared better than others, no nation has escaped the power of COVID-19. We have been forced to rethink and improvise so life can continue. Technology has become a massive part of staying connected, education, and business in a contactless era.

Today, daily life looks much different than how we started the year. If your household has children, most educational institutions offer the choice of in-person (with CDC safeguards) or remote learning from home. Employers who have the resources either alternate staff during the week or have gone to work from home. Some bars sell food in a loophole effort to keep their doors open. Limited seating is available in restaurants. Many have begun to offer delivery or curbside service that previously wasn’t an option.

People are generally home more since events and gatherings over a certain amount are not allowed. We have tossed out the “5-second rule”, hugs, shaking hands, and any other non-immediate family direct contact. Smiles are hidden behind masks, non-emergency medical procedures are put off, and every sneeze is suspicious. Despite the numerous changes to our daily lives due to COVID-19, our continuance to move forward and make progress is a testament to our ability to adapt to change.

Volunteers and Research

Whether it’s helping at a food bank or making masks for those in need, lots of people are joining the effort to help others through volunteering. As researchers race to produce effective therapies and vaccines for COVID-19, volunteers continue to step up and join the fight to end it. Clinical research studies and the volunteers that participate in them help advance ways to detect, treat, and prevent different medical conditions like COVID-19.

Woman, COVID-19, Research volunteer

Without the efforts of study participants, these advancements would not be possible. To learn more about participating in research studies or view currently enrolling options here at Arizona Liver Health, call us at (480) 470-4000, or visit us here.



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2152 S Vineyard Ave Ste 123
Mesa, AZ 85210
480-360-4000


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1601 N Swan Rd
Tucson, AZ 85712
520-445-4000


Call us to see if you or your patient qualify for a clinical trial.